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Endotoxin induced prolonged fever in rats

✍ Scribed by Torbjørn Severinsen; Nils Are Øritsland


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
341 KB
Volume
16
Category
Article
ISSN
0306-4565

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Fever was induced in rats with a single i.p. injection of 30 g/kg E. coli endotoxin. The effect of the alcohol leaf extract of Azadirachta indica was investigated in this model. Pretreatment of rats with the leaf extract (125-375 mg/kg) did not significantly reduce endotoxin-induced fever. The recta