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Endocrine ablation in breast cancer patients who have failed cytotoxic therapy

✍ Scribed by John J. Ferrara; Nancy A. Reiches; John Peter Minton


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
307 KB
Volume
18
Category
Article
ISSN
0022-4790

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## Abstract ## BACKGROUND. Homoharringtonine (HHT) is a cephalotaxus alkaloid that inhibits the synthesis of proteins leading to apoptosis. Intravenous HHT has demonstrated activity in patients with chronic myeloid leukemia (CML) after failure with interferon. ## METHODS. A Phase I study was com