Low tissue enzyme activity seen in breast cancers of patients who fail adjuvant chemotherapy

Higher frequency of gene amplification i

Higher frequency of gene amplification in breast cancer patients who received adjuvant chemotherapy

✍ Ulf Lönn; Sigrid Lönn; Bo Nilsson; Björn Stenkvist 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB 👁 1 views

## BACKGROUND. Amplification of certain genes is involved in resistance to chertiotherapy. The development of such amplification in patients by drug treatment has not yet been established. We have assessed the appearance of gene amplification in breast cancer patients with recurrent disease. One g