✦ LIBER ✦

End-stae dementia in adults with down syndrome

✍ Scribed by Dr. V. Prasher

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 240 KB
Volume: 10
Category: Article
ISSN: 0885-6230
DOI: 10.1002/gps.930101213

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✦ Synopsis

End-stage dementia in adults with Down syndrome has not been fully investigated. Available information, 6 months prior to death, for 20 adults with Down syndrome who had died with Alzheimer's disease was reviewed. A terminal stage of severe intellectual deterioration, marked personality and mood changes, loss of sphincter control, seizure activity, immobility with hypertonia and complete loss of self-care skills was found. These findings have important clinical and service implications.

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