## Abstract ## Objectives To determine the prevalence of dementia in an Irish sample of people with Down's syndrome (DS) and to examine associated clinical characteristics of dementia in this group. ## Method 285 people with DS (Age 35โ74 years, mean ageโยฑโSD 46.5โยฑโ8.2 years) were included in t
Dementia with Lewy bodies in Down's syndrome
โ Scribed by Martine Simard; Robert van Reekum
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 102 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.342
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
The association between Down's syndrome (DS) and Alzheimer's disease is well established. This paper presents a review of the literature, suggesting a possible association between DS and the more recently recognised dementia with Lewy bodies (DLB). Patients with DLB frequently present with changes in affect and behaviour, and in particular with psychotic symptoms. The literature suggests a possible role for atypical neuroleptics in the management of psychosis in DLB. Copyright ยฉ 2001 John Wiley & Sons, Ltd.
๐ SIMILAR VOLUMES
Cognitive decline and dementia affect approximately 30% to 40% of patients with idiopathic Parkinson's disease during the course of their illness. PD-dementia (PDD) and dementia with Lewy bodies (DLB) are second to Alzheimer's disease in causing degenerative dementia in the elderly. The nosological
Objectives. Dementia with Lewy bodies (DLB) is now a well-recognized form of dementia in which psychosis and behavioural disturbance are common. Treatment with conventional neuroleptics is often very poorly tolerated. Olanzapine, a newly introduced atypical neuroleptic which binds to multiple recept