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✦   LIBER   ✦

Encyclopedia of Life Sciences || BH3-only Proteins

✍ Scribed by Happo, Lina

Book ID
120532997
Publisher
John Wiley & Sons, Ltd
Year
2009
Tongue
English
Weight
253 KB
Category
Article
ISBN-13
9780470015902

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✦ Synopsis

Articles In The Fields Of Biochemistry And Physiology, Cell Biology, Developmental Biology, Ecology, Evolution, Genetics, Immunology, Molecular Biology, Neuroscience, Microbiology And Virology, Plant Science, Structural Biology, Science And Society. Includes Index.

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## Abstract Bcl‐2 family proteins play central roles in the regulation of most, if not all, apoptotic pathways, and hence this family plays a critical role in oncogenesis. The Bcl‐2 homology 3 (BH3)‐only members of this family are β€œproapoptotic,” promoting apoptosis by sensing cellular stresses: th