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BH3-only proteins: orchestrating cell death

✍ Scribed by Fletcher, J I; Huang, D C S


Book ID
110017289
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
94 KB
Volume
13
Category
Article
ISSN
1350-9047

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## Abstract Bcl‐2 family proteins play central roles in the regulation of most, if not all, apoptotic pathways, and hence this family plays a critical role in oncogenesis. The Bcl‐2 homology 3 (BH3)‐only members of this family are β€œproapoptotic,” promoting apoptosis by sensing cellular stresses: th