A total synthesis of bengamide E is reported. The synthesis includes the utilization of D-tartrate as the chiral building block, construction of the E-olefin by the Julia protocol, an anti-aldol reaction to generate C-2 and C-3 stereocenters, and coupling of the thioester with caprolactam hydrochlor
✦ LIBER ✦
Enantiospecific Total Synthesis of (−)-Bengamide E
✍ Scribed by Metri, Prashant K.; Schiess, Raphael; Prasad, Kavirayani R.
- Book ID
- 127184868
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 303 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1861-4728
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