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A Chemoenzymatic Total Synthesis of ent -Bengamide E

✍ Scribed by Banwell, Martin G.; McRae, Kenneth J.


Book ID
120243702
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
90 KB
Volume
66
Category
Article
ISSN
0022-3263

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Total synthesis of bengamide E
✍ Wenming Liu; Joanna M Szewczyk; Liladhar Waykole; Oljan Repič; Thomas J Blackloc πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 69 KB

A total synthesis of bengamide E is reported. The synthesis includes the utilization of D-tartrate as the chiral building block, construction of the E-olefin by the Julia protocol, an anti-aldol reaction to generate C-2 and C-3 stereocenters, and coupling of the thioester with caprolactam hydrochlor

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