## Abstract Methyl‐2‐acetamido‐4,6‐di‐__O__‐acetyl‐3‐__S__‐acetyl‐2‐deoxy‐3‐thio‐α‐D‐mannopy‐ranoside has been synthesized by conversion of methyl 2‐amino‐2‐deoxy‐4,6‐__O__‐benzylidene‐α‐D‐altropyranoside into the corresponding 3‐__O__‐methanesulfony1‐2‐__N__‐[(methylthio)thiocarbonyl]derivative fo
Enantiospecific synthesis of (2S,3S,5S)-2-acetamido-2,4-dideoxyhexopyranose (N-acetyl-4-deoxy-D-mannosamine) fromD-glucose
✍ Scribed by Mulzer, Johann ;Seilz, Carsten ;Reutter, Werner
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 432 KB
- Volume
- 1991
- Category
- Article
- ISSN
- 0947-3440
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✦ Synopsis
Abstract
A 14‐step enantiospecific total synthesis (overall yield 6%) of the title compound 1 from the known furanose 4 (derived from D‐glucose) is described.
📜 SIMILAR VOLUMES
Hydroxy-2-penten&lide (5) was synthesized in three stcps starting from mnannitol bidacetonide) (l), via Dglyceraldchydc acetonide (2) by Z-selective Wittig reaction, acid-catalyzed lactonization and crystallization with a total yield of 40%. (S)-S-Hydroxy-2-penten-4-0lide (S), the aglycone of ranun
D e u t e r a t e d a n a b o l i c d r u g s . P a r t 2 S y n t h e s i s o f ( R , S ) -3 , 4 -b i s ( 4-hydroxyphenyl)-[2,2,5,5-d l h e x a n e ( HEX-d a n d (E,E)-3,4-bis(4-hydroxyphenyl)-[2,5-d l h e x a -2 , 4 -d i e n e (DE-d ) 4 4 2 2 G i j s b e r t Zomer, Henk J.C.M. D e r k s a n d H a n