ChemInform Abstract: Stereodivergent Synthesis of (2S,3S,4R,5R)- and (2S,3S,4R,5S)-[3,4,5-D3]Proline Depending on the Substituent of the γ-Lactam Ring.
✍ Scribed by Makoto Oba; Akiko Miyakawa; Kozaburo Nishiyama; Tsutomu Terauchi; Masatsune Kainosho
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 42 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Methoxycyclitol 4 was acetalized in a non-classical one-pot idene moiety was realised in two steps via the corresponding ethylidene acetals 8 and 9; the ethylidene function was procedure with chloral/dicyclohexylcarbodiimide forming the 4-epi derivative 6. The stepwise deprotection of removed with a
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