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Enantioselective Total Synthesis of Aspergillide C

✍ Scribed by Nagasawa, Tomohiro; Kuwahara, Shigefumi


Book ID
120257272
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
106 KB
Volume
11
Category
Article
ISSN
1523-7060

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Total synthesis of (+)-aspergillide C
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The enantioselective total synthesis of aspergillide C, a member of a novel class of 14-membered macrolides isolated from the marine-derived fungus Aspergillus ostianus strain 01F313, has been accomplished employing a highly diastereoselective intramolecular oxy-Michael reaction as the key step.

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