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Enantioselective synthesis of α-bromo acid derivatives and bromohydrins † from tartrate derived bromoacetals

✍ Scribed by Boyes, Scott A.; Hewson, Alan T.


Book ID
120263770
Publisher
Royal Society of Chemistry
Year
2000
Weight
139 KB
Volume
16
Category
Article
ISSN
1472-7781

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ChemInform Abstract: Enantioselective Sy
✍ Scott A. Boyes; Alan T. Hewson 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

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Enantioselective synthesis of α-aminopho
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Chiral ␣-aminophosphonic acid derivatives are efficiently synthesized by asymmetric hydrogenation of the prochiral N-acyl-␣,␤-dehydroaminophosphonates. PROPRAPHOS-Rh-catalysts from readily available (S)-and (R)-Propranolol proved to be suitable in the homogenous reaction affording an enantiomeric ex