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Enantioselective Synthesis of the Papulacandin Ring System: Conversion of the Mannose Diastereoisomer into a Glucose Stereoisomer
β Scribed by Balachari, Devan; O'Doherty, George A.
- Book ID
- 126160339
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 70 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1523-7060
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The functionalized tricyclic nagilactone precursor 19 was synthesized by a route featuring a vinylsilane terminated/1,3-dioxane acetal initiated bicyclization. Relative and absolute stereochemical control were achieved via the optically active pentenolide template 14.