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Enantioselective synthesis of (S)-2-amino-4-phenylbutanoic acid by the hydantoinase method

✍ Scribed by Hsueh-Hsia Lo; Chao-Hung Kao; Dong-Sheng Lee; Teng-Kuei Yang; Wen-Hwei Hsu


Book ID
102073854
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
68 KB
Volume
15
Category
Article
ISSN
0899-0042

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## Abstract A synthesis of [^3^H]__R__‐ and [^3^H]__S__‐4‐amino‐3‐phenylbutanoic acid ([^3^H]__R__‐ and [^3^H]__S__‐β‐phenylGABA) from the unsaturated intermediate by catalytic hydrogenation using tritium gas in the presence of palladium on charcoal is reported. The [^3^H]__R__‐ and [^3^H]__S__‐dia