Enantioselective synthesis of phosphonothrixin and its absolute stereochemistry
โ Scribed by Kazuhiko Nakamura; Shosuke Yamamura
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 121 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The synthesis of both enantiomers of phosphonothrixin is described. On the basis of optical rotation and biological activity, the natural product was determined to have S configuration.
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## Abstract For Abstract see ChemInform Abstract in Full Text.
The structure and absolute stereochemistry of thysanone 3 , a fungal benzoisochromanquinone with potent human rhbzovirus 3C-protease #zhibitoo" activity, is established by the total synthesis of its antipode I from (S)-propylene oxide.