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Enantioselective synthesis of mannostatin A: a new glycoprotein processing inhibitor

✍ Scribed by King, S. Bruce; Ganem, Bruce


Book ID
121681066
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
289 KB
Volume
113
Category
Article
ISSN
0002-7863

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The synthesis of a new fluoro-substituted 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor 2 in high optical purity via addition of the chiral enolate 12 to fluoro aldehyde 82 is described.