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Enantioselective Synthesis of Imperanene, a Platelet Aggregation Inhibitor

โœ Scribed by Shattuck, James C.; Shreve, Cheney M.; Solomon, Sandra E.

Book ID
120630348
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
47 KB
Volume
3
Category
Article
ISSN
1523-7060

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In a search for the inhibitors of platelet aggregation, certain coumarin derivatives were synthesized and evaluated for antiplatelet activity against thrornbin(Thr)-, arachidonic acid(AA)-, collagen(Co1)-, and platelet-activating-factor(PAF)-induced aggregation in washed rabbit platelets. These comp