Enantioselective Synthesis of Aroylalanine Derivatives.
β Scribed by Barry Lygo; Benjamin I. Andrews
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 125 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Addition of a propargylsilane moiety onto chiral cyclic of an allenic amino acid in the acyclic series; however, this isomerization did not take place with the cyclic Ξ±-amino ester iminium ions occurs with a high level of stereoselectivity intermolecularly as well as intramolecularly. This operation
Chiral β£-aminophosphonic acid derivatives are efficiently synthesized by asymmetric hydrogenation of the prochiral N-acyl-β£,β€-dehydroaminophosphonates. PROPRAPHOS-Rh-catalysts from readily available (S)-and (R)-Propranolol proved to be suitable in the homogenous reaction affording an enantiomeric ex
## Abstract An enantioselective route to functionalized 3βoxabicycloβ[3.3.0]octane derivatives which can be used in hydroazulene synthesis is described. The configuration and conformation of the ketone 10 has been determined by ^1^HβNMR spectroscopy and forceβfield calculations.