Enantioselective synthesis of 1,2-, 1,3- and 1,4- aminoalcohols by the addition of dialkylzincs to 1,2-, 1,3- and 1,4- aminoaldehydes
✍ Scribed by Christian Lutz; Volker Lutz; Paul Knochel
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 972 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## Abstract New 5′‐acetyl‐3′‐1,3,4‐thiadiazoliminothymidines **__11, 14__** were prepared, __via__ spontaneous rearrangments, by cycloaddition of 5′‐acetyl‐3′‐deoxy‐3′‐isothiocyanatothymidine **__9__** with 1‐aza‐2‐azoniaallene hexachloantimonates. Similary, 3′‐cyano analogue **__19__** was reacted
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The reaction of N‐aryl‐C‐ethoxycarbonyl nitrilimines with [1,2,4]triazepin‐3,5‐dithione leads to title compounds. The 1,3‐dipolar cycloaddition is completely peri and regioselective. The preferred orientation of addition is predicted correctly by AM~1~ calculation.