Enantioselective Sensors and Biosensors in the Analysis of Chiral Drugs
β Scribed by Aboul-Enein, Hassan Y.; Stefan, Raluca-Ioana
- Book ID
- 121501634
- Publisher
- Taylor and Francis Group
- Year
- 1998
- Tongue
- English
- Weight
- 52 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1040-8347
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Molecular recognition of different enantiomers of a drug has become of increasing importance in the last decade due to the racemic switch strategy adapted by the pharmaceutical industry. Different analytical techniques to carry out enantioselective analysis of chiral compounds have been suggested in
Chiral stationary phases (CSPs) are becoming abundant and extensively used in resolution of drug racemates. The polysaccharide-type CSPs namely the cellulose and amylose derivatives are widely used in the resolution and analysis of racemate drugs by high performance liquid chromagraphy (
We present a method for the enantioselective analysis of albendazole sulfoxide (ABZSO) in plasma for application in clinical pharmacokinetic studies. ABZSO enantiomers were separated on a 5-micron Chiralcel OB-H column (4.6 x 150 mm) using hexane:ethanol (93:7, v/v) as the mobile phase and fluoresce