Enantioselective ring-opening reaction of meso-epoxides with ArSH catalyzed by heterobimetallic Ti–Ga–Salen system

✍ Scribed by Jiangtao Sun; Fang Yuan; Minghua Yang; Yi Pan; Chengjian Zhu

• Book ID: 104096041
• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 166 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.11.060

✦ Synopsis

a Unless otherwise noted, the reaction condition: cyclohexene oxide (1 mmol), PhSH (1.2 mmol), catalyst (10 mol %).

b Isolated yields. c Determined by HPLC with a Daicel Chiralcel OD column. Absolute configurations of the major enantiomers (1S,2S) were assigned by comparison of the rotation values in the literature. d 5 mol % of 3b. e 2 mol % of 3b