𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantioselective reduction of 2-substituted tetrahydropyran-4-ones using Daucus carota plant cells

✍ Scribed by J.S. Yadav; B.V. Subba Reddy; Ch. Sreelakshmi; G.G.K.S. Narayana Kumar; A. Bhaskar Rao

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
135 KB
Volume
49
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Enzymatic reduction of 2-substituted tetrahydropyran-4-ones with Daucus carota, plant cells as biocatalyst occurred in water under extremely mild and environmentally benign conditions giving a 1:1 mixture of diastereoselectively (2R,4S)-and (2S,4S)-2-aryl-or 2-alkyl-tetrahydropyranols in high yields.

📜 SIMILAR VOLUMES

Asymmetric reduction of 2-oxo-4-phenylbu
Asymmetric reduction of 2-oxo-4-phenylbutanoic acid ethyl ester by Daucus carota cell cultures
✍ A. Chadha; M. Manohar; T. Soundararajan; T.S. Lokeswari 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 142 KB

4 novel method to produce (R)-(-)-2-hydroxy-4-phenylbutanow acid ethyl ester lb has been developed. 2-Oxo-4-phe~lbutanoic acid ethyl ester la is reduced to lb ~, the cell cultures of Daucus carota in high enantiomeric excess and yield.

Functionalization of (2S)-Isopropyl-5-io
Functionalization of (2S)-Isopropyl-5-iodo-2,3-dihydro-4(H)-pyrimidin-4-ones by a Suzuki–Miyaura Cross-Coupling Reaction Using Aryltrifluoroborate Salts: Convenient Enantioselective Preparation of α-Substituted β-Amino Acids
✍ Hélio A. Stefani; Monica F. Z. J. Amaral; Gloria Reyes-Rangel; Jorge Vargas-Capo 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 565 KB

## Abstract A simple protocol for the Pd(OAc)~2~‐catalyzed cross‐coupling reaction of 1‐benzoyl‐(2__S__)‐isopropyl‐5‐iodo‐2,3‐dihydro‐4(__H__)‐pyrimidin‐4‐ones with potassium aryltrifluoroborates was developed. The reaction is performed at 110 °C with a ligand‐free catalyst. In all cases, complete