Asymmetric reduction of 2-oxo-4-phenylbutanoic acid ethyl ester by Daucus carota cell cultures

✍ Scribed by A. Chadha; M. Manohar; T. Soundararajan; T.S. Lokeswari

• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Weight: 142 KB
• Volume: 7
• Category: Article
• ISSN: 0957-4166
• DOI: 10.1016/0957-4166(96)00183-8

✦ Synopsis

4 novel method to produce (R)-(-)-2-hydroxy-4-phenylbutanow acid ethyl ester lb has been developed. 2-Oxo-4-phe~lbutanoic acid ethyl ester la is reduced to lb ~, the cell cultures of Daucus carota in high enantiomeric excess and yield.