Enantioselective reduction of 2-substitu
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J.S. Yadav; B.V. Subba Reddy; Ch. Sreelakshmi; G.G.K.S. Narayana Kumar; A. Bhask
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Article
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2008
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Elsevier Science
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French
β 135 KB
Enzymatic reduction of 2-substituted tetrahydropyran-4-ones with Daucus carota, plant cells as biocatalyst occurred in water under extremely mild and environmentally benign conditions giving a 1:1 mixture of diastereoselectively (2R,4S)-and (2S,4S)-2-aryl-or 2-alkyl-tetrahydropyranols in high yields