Enantioselective Recognition of Dopa Enantiomers in the Presence of Ascorbic Acid or Tyrosine

✍ Scribed by Qian Han; Qiao Chen; Yonghua Wang; Juan Zhou; Yingzi Fu

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 309 KB
• Volume: 24
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.201100378

✦ Synopsis

Abstract

A simple sensor was obtained through N‐isobutyryl‐L‐(D)‐cysteine enantiomers self‐assembled monolayer. It was demonstrated that the N‐isobutyryl‐cysteine modified gold electrodes can enantioselectively recognize 3,4‐dihydroxyphenylalanine (dopa) enantiomers. The electrocatalytic behaviors of enantiomers were analyzed with cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Selectivity of the chiral surface was estimated by investigating two mixture enantiomers (dopa‐ascorbic acid and dopa‐tyrosine), it certified that the sensor was only satisfactorily used to specific recognize dopa enantiomers. The possible mechanism for the enantioselective recognition was discussed.