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Determination of Uric Acid in the Presence of Ascorbic Acid Using Poly(3,4-ethylenedioxythiophene)-Modified Electrodes

✍ Scribed by Shanmugam Senthil Kumar; Jayaraman Mathiyarasu; Kanala Lakshminarasimha Phani; Yogendra Kumar Jain; Venkatraman Yegnaraman


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
210 KB
Volume
17
Category
Article
ISSN
1040-0397

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✦ Synopsis


A poly(3,4-ethylenedioxythiophene) (PEDOT) modified glassy carbon electrode (GCE) was used to determine uric acid in the presence of ascorbic acid at physiological pH facilitating a peak potential separation of ascorbic acid and uric acid oxidation (ca. 365 mV), which is the largest value reported so far in the literature. Also, an analytical protocol involving differential pulse voltammetry has been developed using a microchip electrode for the determination of uric acid in the concentration range of 1 to 20 mM in presence of excess of ascorbic acid.


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✍ Minerva Ramírez-Berriozabal; Laura Galicia; Silvia Gutiérrez-Granados; José Sand 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB 👁 2 views

## Abstract Uric acid (UA) was determined in the presence of ascorbic acid (AA) by using a carbon paste electrode modified superficially by a β‐cyclodextrin film (CPE/β‐CD). The surface carbon paste electrode was prepared applying a 30 cycles potential program and using a 1 M HClO~4~+0.01 M β‐CD el