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Enantioselective preparation of allenecarboxylates by asymmetric horner-wadsworth-emmons reaction

✍ Scribed by Kiyoshi Tanaka; Kenji Otsubo; Kaoru Fuji


Book ID
103405963
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
256 KB
Volume
37
Category
Article
ISSN
0040-4039

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Enantioselective Horner–Wadsworth–Emmons
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The enantioselective Horner-Wadsworth-Emmons reaction of 2-fluoro-2-diethylphosphonoacetates with s-symmetric prochiral 2-substituted-1,3-dioxan-5-ones and 4-substituted-cyclohexanones was investigated by employing Sn(OSO 2 CF 3 ) 2 and N-ethylpiperidine in the presence of an external chiral ligand,