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A Catalytic Michael/Horner-Wadsworth-Emmons Cascade Reaction for Enantioselective Synthesis of Thiochromenes

✍ Scribed by Choudhury, Abhijnan Ray; Mukherjee, Santanu


Book ID
120559874
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
525 KB
Volume
355
Category
Article
ISSN
1615-4150

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Enantioselective Horner–Wadsworth–Emmons
✍ Shigeki Sano; Kenji Yokoyama; Rie Teranishi; Motoo Shiro; Yoshimitsu Nagao 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 106 KB

The enantioselective Horner-Wadsworth-Emmons reaction of 2-fluoro-2-diethylphosphonoacetates with s-symmetric prochiral 2-substituted-1,3-dioxan-5-ones and 4-substituted-cyclohexanones was investigated by employing Sn(OSO 2 CF 3 ) 2 and N-ethylpiperidine in the presence of an external chiral ligand,