Enantioselective Horner–Wadsworth–Emmons
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Shigeki Sano; Kenji Yokoyama; Rie Teranishi; Motoo Shiro; Yoshimitsu Nagao
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Article
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2002
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Elsevier Science
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French
⚖ 106 KB
The enantioselective Horner-Wadsworth-Emmons reaction of 2-fluoro-2-diethylphosphonoacetates with s-symmetric prochiral 2-substituted-1,3-dioxan-5-ones and 4-substituted-cyclohexanones was investigated by employing Sn(OSO 2 CF 3 ) 2 and N-ethylpiperidine in the presence of an external chiral ligand,