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Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

✍ Scribed by Saito, Kodai; Akiyama, Takahiko

Book ID: 120610525
Publisher: Royal Society of Chemistry
Year: 2012
Tongue: English
Weight: 905 KB
Volume: 48
Category: Article
ISSN: 1359-7345
DOI: 10.1039/C2CC31486J

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## Abstract A highly enantioselective Michael addition of 3‐aryloxindole to phenyl vinyl sulfone catalyzed by a quinine‐derived bifunctional amine–thiourea‐bearing sulfonamide as multiple hydrogen‐bonding donor catalyst has been investigated. The corresponding adducts, which contain a chiral quater