ChemInform Abstract: Enantioselective Conjugate Addition of Both Aromatic Ketones and Acetone to Nitroolefins Catalyzed by Chiral Primary Amines Bearing Multiple Hydrogen-Bonding Donors.
β Scribed by Zhong-Wen Sun; Fang-Zhi Peng; Ze-Qian Li; Li-Wei Zou; Shao-Xiong Zhang; Xiang Li; Zhi-Hui Shao
- Book ID
- 112048840
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 46 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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A new efficient catalyst system for the asymmetric addition of acetylacetone to nitroolefins using a chiral bifunctional organocatalyst bearing multiple hydrogen-bonding donors was developed. When using the organocatalyst 2c derived from natural cinchona alkaloid in optimal conditions, up to 98% che
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