Enantioselective Conjugate Addition of Both Aromatic Ketones and Acetone to Nitroolefins Catalyzed by Chiral Primary Amines Bearing Multiple Hydrogen-Bonding Donors
β Scribed by Sun, Zhong-Wen; Peng, Fang-Zhi; Li, Ze-Qian; Zou, Li-Wei; Zhang, Shao-Xiong; Li, Xiang; Shao, Zhi-Hui
- Book ID
- 115543690
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 424 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A new efficient catalyst system for the asymmetric addition of acetylacetone to nitroolefins using a chiral bifunctional organocatalyst bearing multiple hydrogen-bonding donors was developed. When using the organocatalyst 2c derived from natural cinchona alkaloid in optimal conditions, up to 98% che
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