Enantioselective Hydrogenation of β-Acylamino Acrylates Catalyzed by Rhodium(I)-Monophosphite Complexes.
✍ Scribed by Thomas Jerphagnon; Jean-Luc Renaud; Patrice Demonchaux; Amadeo Ferreira; Christian Bruneau
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 144 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The enantioselective hydrogenation of β‐(acyloxy)‐ and β‐(acylamino)vinylphosphonates with rhodium catalysts based on chiral phosphane‐phosphite ligands has been studied. In the case of the β‐(acyloxy)vinylphosphonates, the reaction also produces an achiral phosphonate resulting from th
## Abstract The Rh complex (RPO) efficiently promotes the asymmetric hydrogenation of title phosphonates giving synthetically and biologically important β‐functionalized phosphonates in high optical purity.
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