Enantioselective hantzsch dihydropyridine synthesis via metalated chiral alkyl acetoacetate hydrazones1
✍ Scribed by Dieter Enders; Stephan Müller; Ayhan S. Demir
- Book ID
- 104217808
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 232 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
a-Benzyloxy aldehydes and a-acetoxy ketones 4 of high enantiomeric purity are prepared in good overall yields via oxaziridine mediated hydroxylation of chiral hydrazone azaenolates. As auxiliaries novel proline derived hydrazine reagents 5 are used. The importance of a-hydroxy carbonyl compounds as
Oiastereoselective addition of organolithium reagents on hydrazones vicinal to chiral cyclic acetals provide chiral hydrazinoacetals from which optically active aminoacetals and aminoacids can be prepared. Recently the syntheses of optically active amines involving the addition of organometallic rea