β Scribed by Dieter Enders; Herbert Eichenauer
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
a-Benzyloxy aldehydes and a-acetoxy ketones 4 of high enantiomeric purity are prepared in good overall yields via oxaziridine mediated hydroxylation of chiral hydrazone azaenolates. As auxiliaries novel proline derived hydrazine reagents 5 are used. The importance of a-hydroxy carbonyl compounds as
Oiastereoselective addition of organolithium reagents on hydrazones vicinal to chiral cyclic acetals provide chiral hydrazinoacetals from which optically active aminoacetals and aminoacids can be prepared. Recently the syntheses of optically active amines involving the addition of organometallic rea
Asymmetric ot-sulfenylation of lithiated SAMP/RAMP hydrazoncs (3")-2 with disulfides afforded tz-thiolated hydrazones (S,R)-3 in good yields (48-87%) and high diastcreomeric excesses (91-96%). Subsequent oxidative cleavage or acidic hydrolysis of the hydrazones furnished a-thiolated ketones (R)-4a.d