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Enantioselective bioreduction of 2-fluoro-2-alken-1-ols mediated by Saccharomyces cerevisiae

✍ Scribed by Fan Luo; Dengfu Lu; Yuefa Gong


Book ID
113804819
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
275 KB
Volume
70
Category
Article
ISSN
1381-1177

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Highly enantioselective bioreduction of
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Biocatalytic reduction of 2-fluorocinnamyl alcohols mediated by Saccharomyces cerevisiae was investigated in phosphate buffer solutions. Product analysis clearly showed that (S)-2-fluoro-3-arylpropanols were afforded in high yields with up to 92% ee value.