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Enantioselective Addition of Vinylzinc Reagents to Aldehydes Catalyzed by Modular Ligands Derived from Amino Acids

✍ Scribed by Richmond, Meaghan L.; Sprout, Christopher M.; Seto, Christopher T.


Book ID
126087892
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
136 KB
Volume
70
Category
Article
ISSN
0022-3263

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Modular amino acid amide chiral ligands
✍ Shaohua Gou; Zhongbin Ye; Jing Chang; Guangjun Gou; Mingming Feng πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 129 KB πŸ‘ 2 views

## Abstract Enantioselective addition of diethylzinc to a series of aromatic aldehydes was developed using a modular amino acid amide chiral ligand (2__S__)‐3‐phenyl‐__N__‐((__R__)‐1‐phenyl‐ethyl)‐2‐(tosylamino)propanamide without using titanium complex. The catalytic system employing 10 mol% of 1g