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Modular amino acids and β-amino alcohol-based chiral ligands for enantioselective addition of diethylzinc to aromatic aldehydes

✍ Scribed by Shaohua Gou; Zhongbin Ye; Guangjun Gou; Mingming Feng; Jing Chang


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
159 KB
Volume
25
Category
Article
ISSN
0268-2605

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Modular amino acid amide chiral ligands
✍ Shaohua Gou; Zhongbin Ye; Jing Chang; Guangjun Gou; Mingming Feng 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 1 views

## Abstract Enantioselective addition of diethylzinc to a series of aromatic aldehydes was developed using a modular amino acid amide chiral ligand (2__S__)‐3‐phenyl‐__N__‐((__R__)‐1‐phenyl‐ethyl)‐2‐(tosylamino)propanamide without using titanium complex. The catalytic system employing 10 mol% of 1g