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Enantioselective addition of oxindoles to aliphatic α,β-unsaturated aldehydes

✍ Scribed by Natalia Bravo; Ignasi Mon; Xavier Companyó; Andrea-Nekane Alba; Albert Moyano; Ramon Rios

Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
256 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis

A highly enantioselective organocatalytic oxindole addition to a,b-unsaturated aldehydes is reported. The reaction is catalyzed by simple and commercially available chiral secondary amines, affording the corresponding adducts with good yields and with moderate diastereoselectivities.

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