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Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by γ-Amino Alcohols Derived from (+)- and (-)-α-Pinene.

✍ Scribed by Zsolt Szakonyi; Arpad Balazs; Tamas A. Martinek; Ferenc Fueloep


Publisher
John Wiley and Sons
Year
2006
Weight
22 KB
Volume
37
Category
Article
ISSN
0931-7597

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Enantioselective addition of diethylzinc
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## Abstract β‐Amino alcohols derived from (1__R__,2__S__)‐norephedrine were synthesized and used as ligands in the catalytic enantioselective diethylzinc addition to benzaldehydes. __N__‐alkylated (1__R__,2__S__)‐norephedrine‐based derivative 3a gave the highest enantioselectivity. The effects of d

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