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ChemInform Abstract: Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by β-Amino Alcohols Derived from (1R,2S)-Norephedrine.

✍ Scribed by Dilek Isik Tasgin; Canan Unaleroglu


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
41
Category
Article
ISSN
0931-7597

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Abstract

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Enantioselective addition of diethylzinc
✍ Dilek Isik Tasgin; Canan Unaleroglu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

## Abstract β‐Amino alcohols derived from (1__R__,2__S__)‐norephedrine were synthesized and used as ligands in the catalytic enantioselective diethylzinc addition to benzaldehydes. __N__‐alkylated (1__R__,2__S__)‐norephedrine‐based derivative 3a gave the highest enantioselectivity. The effects of d