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Enantiomeric interaction of flurbiprofen in the rat

✍ Scribed by Brian W. Berry; Fakhreddin Jamali


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
368 KB
Volume
78
Category
Article
ISSN
0022-3549

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Dose-dependency of flurbiprofen enantiom
✍ Fakhreddin Jamali; Brian W. Berry; Matthew R. Wright πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 394 KB πŸ‘ 1 views

Flurbiprofen is a chiral 2-arylpropionate used clinically as a racemate. Previously a significant pharmacokinetic interaction between the enantiomers of flurbiprofen has been reported in both rats and humans. The possible mechanism for this interaction was believed to involve competitive protein bin

Stereospecific evaluation of sotalol pha
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## Abstract Sotalol (STL) is a chiral β‐adrenergic blocking drug, which is useful clinically as the racemate in treating hypertension, and is also useful as a class III antiarrhythmic when administered as the pure S‐enantiomer. Utilizing a stereospecific high‐performance liquid chromatographic (HPL