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Enantiomer separation by capillary SFC and GC on immobilized permethyl-β-cyclodextrin: A systematic comparison

✍ Scribed by Dieter Schmalzing; Graeme J. Nicholson; Martin Jung; Volker Schurig

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
346 KB
Volume
4
Category
Article
ISSN
1040-7685

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✦ Synopsis

Abstract

Immobilized permethyl‐β‐cyclodextrin was used for enantiomer separation by capillary supercritical fluid chromatography and gas chromatography. The influences of pressure and temperature on chiral separation factors, α, and capacity factors, k, have been studied for four representative racemic solutes. The enantioselectivities in supercritical fluid chromatography and gas chromatography are compared. Solvation effects by supercritical carbon dioxide are discussed.

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