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Enantio-differentiating hydrogenation of methyl acetoacetate over modified nickel catalysts: effects of nickel dispersion on the enantio-selectivity of catalysts

โœ Scribed by Donghyun Jo; Jae Sung Lee; Kyung Hee Lee


Book ID
111759725
Publisher
Springer Netherlands
Year
2004
Tongue
English
Weight
483 KB
Volume
30
Category
Article
ISSN
0922-6168

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Application of an in situ modification o
โœ Tsutomu Osawa; Yuka Hayashi; Atsushi Ozawa; Tadao Harada; Osamu Takayasu ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 82 KB

In situ modification ((R,R)-tartaric acid and NaBr were directly added to the reaction media) of fine Ni powder (FNiP) and reduced Ni catalysts was applied to the enantio-differentiating hydrogenation of methyl acetoacetate (MAA). The high optical yield of 89% was attained by the reduced Ni catalyst