Emerging Technology Platforms for Stem Cells

✍ Scribed by Uma Lakshmipathy, Jonathan D. Chesnut, Bhaskar Thyagarajan

• Publisher: John Wiley & Sons
• Year: 2009
• Tongue: English
• Leaves: 526
• Edition: 1
• Category: Library

✦ Synopsis

This book focuses on practical applications for using adult and embryonic stem cells in the pharmaceutical development process. It emphasizes new technologies to help overcome the bottlenecks in developing stem cells as therapeutic agents. A key reference for professionals working in stem cell science, it presents the general principles and methodologies in stem cell research and covers topics such as derivitization and characterization of stem cells, stem cell culture and maintenance, stem cell engineering, applications of high-throughput screening, and stem cell genetic modification with their use for drug delivery.

✦ Table of Contents

Frontmatter.pdf......Page 1
Color Plates.pdf......Page 16
Part none: VI......Page 0
01- Derivation Methods for Human Embryonic Stem Cells Past, Present, and Future.pdf......Page 40
02- Isolation of Human Embryonic Stem Cells from Various Stages of the Human Embryo.pdf......Page 57
03- Derivation of Stem Cells from Epiblasts ý.pdf......Page 66
04- Derivation of Embryonic Stem Cells from Parthenogenetic Eggs ý.pdf......Page 75
05- Reprogramming Developmental Potential ý.pdf......Page 86
06- Adult Stem Cells and Their Role in Endogenous Tissue Repair ý.pdf......Page 121
07- Greater Differentiation Potential of Adult Stem Cells ý.pdf......Page 143
08- Cancer Stem Cells ý.pdf......Page 161
09- Large-Scale Production of Adult Stem Cells for Clinical Use.pdf......Page 184
10- Genetic and Epigenetic Features of Stem Cells ý.pdf......Page 200
11- Directed Differentiation of Embryonic Stem Cells ý.pdf......Page 233
12- Identification of Signaling Pathways Involved During Differentiation ý.pdf......Page 264
13- Media and Extra Cellular Matrix Requirements for Large-Scale ESC Growth ý.pdf......Page 277
14- Automated Method for Embryonic Stem Cell Culture ý.pdf......Page 302
15- Quantitative 2D Imaging of Human Embryonic Stem Cells ý.pdf......Page 309
16- Nanobiotechnology for Stem Cell Culture and Maintenance.pdf......Page 317
17- Engineering Microenvironments to Control Stem Cell Functions.pdf......Page 337
18- Improved Lentiviral Gene Delivery Tools for Stem Cells.pdf......Page 353
19- Sleeping Beauty-Mediated Transposition in Stem Cells.pdf......Page 366
20- PhiC31 Integrase for Modification of Stem Cells.pdf......Page 388
21- Cell Engineering Using Integrase and Recombinase Systems.pdf......Page 404
22- Human Embryonic Stem Cell-Derived Cardiomyocytes for Cell Therapy and Drug Discovery.pdf......Page 420
23- Human Embryonic Stem Cells in Drug Discovery.pdf......Page 440
24- Characterization and Culturing of Adipose-Derived Precursor Cells.pdf......Page 461
25- Bringing Mesenchymal Stem Cells into the Clinic.pdf......Page 485
Index.pdf......Page 504