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Elimination of transamination side product by the use of dCAc methylphosphonamidite in the synthesis of oligonucleoside methylphosphonates

✍ Scribed by M.P Reddy; Firdous Farooqui; Naeem B Hanna


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
196 KB
Volume
37
Category
Article
ISSN
0040-4039

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✦ Synopsis


The transamination side product formed by the use of dC bz or dC *~ methylphosphonamidite upon treatment with ethylenediamine has been eliminated by the use of dC Ac methylphosphonamidite. The synthesis and characterization of DMT dC Ac methylphosphonamidite is described.


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