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Elevation of gamma delta T lymphocytes in peripheral blood and livers of patients with primary sclerosing cholangitis and other autoimmune liver diseases

โœ Scribed by EB Martins; AK Graham; RW Chapman; KA Fleming


Book ID
118686191
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
346 KB
Volume
23
Category
Article
ISSN
0270-9139

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Primary sclerosing cholangitis (PSC) is a chronic cho-may not be their main mechanism of antigen recognilestatic liver disease that is possibly an autoimmune distion. Evidence suggests that they may recognize antiease. Although gd T cells represent a small proportion gen presented by nonpolymorphic

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Using monoclonal antibodies to surface antigens, we typed and quantitated the mononuclear cells (MNCs) infiltrating liver tissues from 23 patients with primary sclerosing cholangitis. The circulating T lymphocytes were also enumerated by flow cytometry in 12 of these patients. In blood, T lymphocyte