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Elevated expression of MMP-13 and TIMP-1 in head and neck squamous cell carcinomas may reflect increased tumor invasiveness

✍ Scribed by Nil Culhaci; Kubilay Metin; Eray Copcu; Emel Dikicioglu


Book ID
115010571
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
338 KB
Volume
4
Category
Article
ISSN
1471-2407

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## Background: Serine proteases have important roles in tumor invasion and metastasis, and their inhibitors, serine protease inhibitors (serpins), are attractive targets for therapeutic strategies. on chromosome 18q21, there is a cluster of serpins: maspin, headpin, and squamous cell carcinoma anti