The multistep assay of specific catechol-O-methyltransferase (COMT) activity in human erythrocytes was validated. Enzyme preparations from lysed erythrocytes were incubated with a substrate (3,4-dihydroxybenzoic acid) in the presence of Mg2+ and S-adenosylmethionine. The reaction products (vanillic
Electrophoretic analysis of low and high activity forms of catechol-O-methyltransferase in human erythrocytes
β Scribed by Mark H. Grossman; Carol Szumlanski; James B. Littrell; Ronald Weinstein; Richard M. Weinshilboum
- Book ID
- 118345571
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 766 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0024-3205
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