✦ LIBER ✦

Electrophilic amination: Enantioselective syntheses of d-allothreonine and l-threonine

✍ Scribed by J.P Genet; S Juge; S Mallart

Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 200 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)82449-1

No coin nor oath required. For personal study only.

✦ Synopsis

Starting from inexpensive polyhydroxybutanoate (PHB), D-allothreonine 1 and L-threonine 2 were synthetized by a sequence involving a diastereoselective electrophilic amination. When (%I 3-hydroxybutanoic acid was protected as dioxanone? very good yield (>95 %I and high diastereomeric excess (>99 %) were obtained in the amination step.

📜 SIMILAR VOLUMES

Enantioselective syntheses of α-amino-β-

Enantioselective syntheses of α-amino-β-hydroxy acids, [15N]-L-allothreonine and [15N]-L-threonine

✍ Andrew Sutherland; Christine L. Willis 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 207 KB

Stereoselective syntheses of protected D

Stereoselective syntheses of protected D-threonine and L-allo-threonine

✍ Richard F.W. Jackson; Nicholas J. Palmer; Martin J. Wythes 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 166 KB

Synthesis of δ-(l-α-aminoadipoyl)-l-cyst

Synthesis of δ-(l-α-aminoadipoyl)-l-cysteinyl-d-(O-methyl)-d-allothreonine a substrate for isopenicillin-N synthase and its O-methyl-d-threonine epimer

✍ Sigthór Pétursson; Jack E Baldwin 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 491 KB

The paper describes the synthesis of two epimeric tdpeptides &(L-cx-aminoadipoyl)-L-cysteinyI-D-(Omethyl)-D-threonine (13) and &(L-ct-aminoadipoyl)-L-cysteinyl-D-(O-methyl)-D-allothreonine ( 14), modified substrates for the isopenicillin-N synthase enzyme. The D-allothreonine tripeptide ( 14) has be

ChemInform Abstract: Synthesis of δ-(L-α

ChemInform Abstract: Synthesis of δ-(L-α-Aminoadipoyl)-L-cysteinyl-D- (O-methyl)-D-allothreonine a Substrate for Isopenicillin-N Synthase and Its O-Methyl-D-threonine Epimer.

✍ S. PETURSSON; J. E. BALDWIN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB

ChemInform Abstract: Syntheses of Four D

ChemInform Abstract: Syntheses of Four D- and L-Hexoses via Diastereoselective and Enantioselective Dihydroxylation Reactions.

✍ Joel M. Harris; Mark D. Keraenen; Hang Nguyen; Victor G. Young; George A. O'Dohe 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 35 KB

ChemInform Abstract: Syntheses of D- and

ChemInform Abstract: Syntheses of D- and L-Mannose, Gulose, and Talose via Diastereoselective and Enantioselective Dihydroxylation Reactions.

✍ Joel M. Harris; Mark D. Keranen; George A. O'Doherty 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB